Structure of PDB 4e4h Chain B

Receptor sequence
>4e4hB (length=458) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSPLRRVLAELNRIPSSRRRAARLFEWLIAPMPPDHFYRRLWEREAVLV
RRQDHTYYQGLFSTADLDSMLRNEEVQFGQHLDAARYINGRRETLNPPGR
ALPAAAWSLYQAGCSLRLLCPQAFSTTVWQFLAVLQEQFGSMAGSNVYLT
PPNSQGFAPHYDDIEAFVLQLEGRKLWRVYRPRAPTEELALTSSPNFSQD
DLGEPVLQTVLEPGDLLYFPRGFIHQAECQDGVHSLHLTLSTYQRNTWGD
FLEAILPLAVQAAMEENVEFRRGLPRDFMDYMGAQHSDSKDPRRTAFMEK
VRVLVARLGHFAPVDAVADQRAKDFIHDSLPPVLTDRERALSVYGLPIRW
EAGEPVNVGAQLTTETEVHMLQDGIARLVGEGGHLFLYYTVENSRVYHLE
EPKCLEIYPQQADAMELLLGSYPEFVRVGDLPCDSVEDQLSLATTLYDKG
LLLTKMPL
3D structure
PDB4e4h tructural Basis for Tetramerization-dependent Gene Repression by Histone Demethylase NO66
ChainB
Resolution2.28 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.27: [histone H3]-dimethyl-L-lysine(36) demethylase.
1.14.11.79: protein-L-histidine (3S)-3-hydroxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE B H340 D342 H405 H160 D162 H225
External links
PDB RCSB:4e4h, PDBe:4e4h, PDBj:4e4h
PDBsum4e4h
PubMed
UniProtQ9H6W3|RIOX1_HUMAN Ribosomal oxygenase 1 (Gene Name=RIOX1)

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