Structure of PDB 4e41 Chain B

Receptor sequence
>4e41B (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
RPRFLWQLKFECHFFNGTERVRLLERCIYNQEESVRFDSDVGEYRAVTEL
GRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRRVEPKVTVYP
SNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDWTFQTLVML
ETVPRSGEVYTCQVEHPSVTSPLTVEWRA
3D structure
PDB4e41 Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B L11 F13 D57 Y60 W61 R71 Y78 N82 V85 L8 F10 D54 Y57 W58 R68 Y75 N79 V82
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:4e41, PDBe:4e41, PDBj:4e41
PDBsum4e41
PubMed
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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