Structure of PDB 4drj Chain B

Receptor sequence
>4drjB (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
MDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLKET
SFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRISKQ
3D structure
PDB4drj Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RAP B L2031 S2035 F2039 T2098 Y2105 F2108 L13 S17 F21 T80 Y87 F90 BindingDB: IC50=>10000nM,Kd=0.600000nM
Gene Ontology
Molecular Function
GO:0044877 protein-containing complex binding

View graph for
Molecular Function
External links
PDB RCSB:4drj, PDBe:4drj, PDBj:4drj
PDBsum4drj
PubMed23358420
UniProtP42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR (Gene Name=MTOR)

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