Structure of PDB 4dri Chain B

Receptor sequence
>4driB (length=96) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMDPEFMEMWHEGLEEASRLYFGERNVKGMFEVLEPLHAMMERGPQTLK
ETSFNQAYGRDLMEAQEWCRKYMKSGNVKDLTQAWDLYYHVFRRIS
3D structure
PDB4dri Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin.
ChainB
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RAP B L2031 S2035 F2039 T2098 Y2105 F2108 L15 S19 F23 T82 Y89 F92 BindingDB: IC50=>10000nM,Kd=0.600000nM
Gene Ontology
Molecular Function
GO:0044877 protein-containing complex binding

View graph for
Molecular Function
External links
PDB RCSB:4dri, PDBe:4dri, PDBj:4dri
PDBsum4dri
PubMed23358420
UniProtP42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR (Gene Name=MTOR)

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