Structure of PDB 4dpq Chain B

Receptor sequence
>4dpqB (length=307) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
NTDDIKALRVITAIKTPYLPDGRFDLEAYDDLVNIQIQNGAEGVIVGGTT
GEGQLMSWDEHIMLIGHTVNCFGGSIKVIGNTGSNSTREAIHATEQGFAV
GMHAALHINPYYGKTSIEGLIAHFQSVLHMGPTIIYNVPGRTGQDIPPRA
IFKLSQNPNLAGVKECVGNKRVEEYTENGVVVWSGNDDECHDSRWDYGAT
GVISVTSNLVPGLMRKLMFEGRNSSLNSKLLPLMAWLFHEPNPIGINTAL
AQLGVSRPVFRLPYVPLPLSKRLEFVKLVKEIGREHFVGEKDVQALDDDD
FILIGRY
3D structure
PDB4dpq Characterisation of the first enzymes committed to lysine biosynthesis in Arabidopsis thaliana
ChainB
Resolution2.202 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T107 Y170 Y194 R199 K222 I261
Catalytic site (residue number reindexed from 1) T49 Y112 Y136 R141 K164 I203
Enzyme Commision number 4.3.3.7: 4-hydroxy-tetrahydrodipicolinate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LYS B N143 E147 N85 E89
BS02 LYS B G111 M114 W116 H119 Y169 G53 M56 W58 H61 Y111
Gene Ontology
Molecular Function
GO:0008840 4-hydroxy-tetrahydrodipicolinate synthase activity
GO:0016829 lyase activity
Biological Process
GO:0009085 lysine biosynthetic process
GO:0009089 lysine biosynthetic process via diaminopimelate
GO:0019877 diaminopimelate biosynthetic process
Cellular Component
GO:0009507 chloroplast

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Biological Process
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Cellular Component
External links
PDB RCSB:4dpq, PDBe:4dpq, PDBj:4dpq
PDBsum4dpq
PubMed22792278
UniProtQ9FVC8|DAPA2_ARATH 4-hydroxy-tetrahydrodipicolinate synthase 2, chloroplastic (Gene Name=DHDPS2)

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