Structure of PDB 4dma Chain B

Receptor sequence
>4dmaB (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
KNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADR
ELVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKL
LFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSII
LLNSGVYTFDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKAKNVVPLYDLLLEMLDAHR
3D structure
PDB4dma Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors.
ChainB
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I1358 K1362 L1372 V1376 E1380 D1538 L1539 E1542 I56 K60 L70 V74 E78 D225 L226 E229
BS02 0L8 B T1347 A1350 E1353 M1421 H1524 L1525 L1540 T45 A48 E51 M119 H211 L212 L227
External links
PDB RCSB:4dma, PDBe:4dma, PDBj:4dma
PDBsum4dma
PubMed22355136
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]