Structure of PDB 4dki Chain B

Receptor sequence
>4dkiB (length=632) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
SKDKEINNTIDAIEDKNFKQVYKDSSYISKSDNGEVEMTERPIKIYNSLG
VKDINIQDRKIKKVSKNKKRVDAQYKIKTNYGNIDRNVQFNFVKEDGMWK
LDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELANTGTAYEIGIV
PKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMDEYL
SDFAKKFHLTTNETESRNYPLEKATSHLLGYVGPINSEELKQKEYKGYKD
DAVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDI
QLTIDAKVQKSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYG
MSNEEYNKLTEDKKEPLLNKFQITTSPGSTQKILTAMIGLNNKTLDDKTS
YKIDGKGWQKDKSWGGYNVTRYEVVNGNIDLKQAIESSDNIFFARVALEL
GSKKFEKGMKKLGVGEDIPSDYPFYNAQISKNLDNEILLADSGYGQGEIL
INPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISKENINLLTDGM
QQVVNKTHKEDIYRSYANLIGKSGTAELKRQIGWFISYDKDNPNMMMAIN
VKDVMASYNAKISGKVYDELYENGNKKYDIDE
3D structure
PDB4dki Structural Insights into the Anti-methicillin-resistant Staphylococcus aureus (MRSA) Activity of Ceftobiprole.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RB6 B S403 K406 Y446 S462 N464 Y519 Q521 S598 G599 T600 E602 S379 K382 Y422 S438 N440 Y494 Q496 S573 G574 T575 E577
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
GO:0071972 peptidoglycan L,D-transpeptidase activity
Biological Process
GO:0046677 response to antibiotic
GO:0071555 cell wall organization
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4dki, PDBe:4dki, PDBj:4dki
PDBsum4dki
PubMed22815485
UniProtA0A0H2WXF8

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