Structure of PDB 4dcx Chain B

Receptor sequence
>4dcxB (length=497) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
DEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKS
WTHSEDGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLEL
ANQIVDVKALSKTELQITLKSAYYPFLQELALPRPFRFIAPSQFKNHETM
NGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPT
TRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLAL
NTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANL
GLKPSQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALS
KSMAEIIQADMRQIGADVSLIGEEESSIYARQRDGRFGMIFHRTWGAPYD
PHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDETQRQALYRD
ILTRLHDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKPV
3D structure
PDB4dcx The structure of the periplasmic nickel-binding protein NikA provides insights for artificial metalloenzyme design.
ChainB
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 L2D B Y22 M27 W100 R137 W398 Y402 H416 Y19 M24 W97 R134 W395 Y399 H413
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016151 nickel cation binding
GO:0020037 heme binding
GO:0046914 transition metal ion binding
GO:0051540 metal cluster binding
GO:1904680 peptide transmembrane transporter activity
Biological Process
GO:0015675 nickel cation transport
GO:0015833 peptide transport
GO:0050919 negative chemotaxis
GO:0055085 transmembrane transport
GO:0098716 nickel cation import across plasma membrane
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4dcx, PDBe:4dcx, PDBj:4dcx
PDBsum4dcx
PubMed22526565
UniProtP33590|NIKA_ECOLI Nickel-binding periplasmic protein (Gene Name=nikA)

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