Structure of PDB 4d7l Chain B

Receptor sequence
>4d7lB (length=212) Species: 257309 (Corynebacterium diphtheriae NCTC 13129) [Search protein sequence]
PRLVEEKDALKGGPHPVLPNPQPHAVLGTLRGQPGTETIYIGIGCYWGAE
KLFWETPGVVYTSVGFAGGITPNPTYRETCTGRTNHTEIVEVVYDPTQVT
FDELVVKAMEAHDPTQGYRQGNDTGTQYRSAIYTAGPNAEQQAQRAREIV
EHYAPKLAAAGLGRITTEILPLASTPAGEYYMAEDEHQQYLHKNPLGYCP
HHSTGVACGIPE
3D structure
PDB4d7l Corynebacterium Diphtheriae Methionine Sulfoxide Reductase a Exploits a Unique Mycothiol Redox Relay Mechanism.
ChainB
Resolution1.895 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C52 Y83 E95 D130 Y135 C206 C215
Catalytic site (residue number reindexed from 1) C45 Y76 E88 D123 Y128 C199 C208
Enzyme Commision number 1.8.4.11: peptide-methionine (S)-S-oxide reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CAC B C52 Y53 W54 Y83 E95 Y135 P207 C45 Y46 W47 Y76 E88 Y128 P200
Gene Ontology
Molecular Function
GO:0008113 peptide-methionine (S)-S-oxide reductase activity
GO:0016491 oxidoreductase activity
GO:0033744 L-methionine:thioredoxin-disulfide S-oxidoreductase activity
GO:0036456 L-methionine-(S)-S-oxide reductase activity
Biological Process
GO:0034599 cellular response to oxidative stress
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4d7l, PDBe:4d7l, PDBj:4d7l
PDBsum4d7l
PubMed25752606
UniProtQ6NEL2|MSRA_CORDI Peptide methionine sulfoxide reductase MsrA (Gene Name=msrA)

[Back to BioLiP]