Structure of PDB 4d52 Chain B

Receptor sequence

>4d52B (length=314)

STPGAQQVLFRTGIAAVNSTNHLRVYFQDVYGSIRESLYEGSWANGTEKN
VIGNAKLGSPVAATSKELKHIRVYTLTEGNTLQEFAYDSGTGWYNGGLGG
AKFQVAPYSCIAAVFLAGTDALQLRIYAQKPDNTIQEYMWNGDGWKEGTN
LGGALPGTGIGATSFRYTDYNGPSIRIWFQTDDLKLVQRAYDPHKGWYPD
LVTIFDRAPPRTAIAATSFGAGNSSIYMRIYFVNSDNTIWQVCWDHGKGY
HDKGTITPVIQGSEVAIISWGSFANNGPDLRLYFQNGTYISAVSEWVWNR
AHGSQLGRSALPPA

3D structure

• PDB: 4d52 Structural Insights Into Aspergillus Fumigatus Lectin Specificity: Afl Binding Sites are Functionally Non-Equivalent.
• Chain: B
• Resolution: 1.76 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	B	C244 D246 H252	C243 D245 H251
BS02	GXL	B	R25 E37 L69 Y88	R24 E36 L68 Y87
BS03	GXL	B	R73 E85 G98 L123 L125 W141 W146	R72 E84 G97 L122 L124 W140 W145
BS04	GXL	B	R126 E138 T150 Y192	R125 E137 T149 Y191
BS05	GIV	B	R25 E37 L69 Y88	R24 E36 L68 Y87
BS06	GIV	B	R126 E138 M140 T150 Y192	R125 E137 M139 T149 Y191
BS07	GIV	B	N22 Y40 R282 E296	N21 Y39 R281 E295

Gene Ontology

Molecular Function

• GO:0030246 carbohydrate binding
• GO:0046872 metal ion binding

Biological Process

• GO:0008150 biological_process

External links

• PDB: RCSB:4d52, PDBe:4d52, PDBj:4d52
• PDBsum: 4d52
• PubMed: 25760594
• UniProt: Q4WW81|LECF_ASPFU Fucose-specific lectin (Gene Name=fleA)