Structure of PDB 4d50 Chain B

Receptor sequence
>4d50B (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMVTEQEVDAIGQTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQ
AFDDDSALLKHELAYCLGQMQDARAIPMLVDVLQDTRQEPMVRHEAGEAL
GAIGDPEVLEILKQYSSDPVIEVAETCQLAVRRLEWLQQHGGEPAAGPYL
SVDPAPPAEERDVGRLREALLDESRPLFERYRAMFALRNAGGEEAALALA
EGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHECAEA
LGAIARPACLAALQAHADDPERVVRESCEVALDMYEHETG
3D structure
PDB4d50 Crystal Structure of the Peroxo-Diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination.
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.99.29: deoxyhypusine monooxygenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FE B H89 E90 H207 H94 E95 H212
BS02 FE B H56 H240 E241 H61 H245 E246
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0005506 iron ion binding
GO:0005515 protein binding
GO:0019135 deoxyhypusine monooxygenase activity
GO:0046872 metal ion binding
Biological Process
GO:0008612 peptidyl-lysine modification to peptidyl-hypusine
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4d50, PDBe:4d50, PDBj:4d50
PDBsum4d50
PubMed25865244
UniProtQ9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase (Gene Name=DOHH)

[Back to BioLiP]