Structure of PDB 4czy Chain B

Receptor sequence
>4czyB (length=403) Species: 5141 (Neurospora crassa) [Search protein sequence]
IPKDRRENLQKKLFHMQQLLPNSGLPNLDRWHSLFPLDTKATRNSTCFGY
PSWMYKAQNNKNGRHFALRRIEGYRLTNEKAILNVTKEWKKIINANIVTV
HEAFTTEFFGDSSLIFVYDFHPLSETLYDHHFPPNRNTNKIPENLLWSYV
CQIANALLAIHNAKLAARCLELSKIIWENNRIRLAACSILDVLHHDSPNR
KTIEELQQEDFVKFGRIILALATNTPTLNFNNIDAALATIVPRYSTQLRG
VLEWLIKPSAPGETKTVETLLGGITTHLANFANFVMQESDEKEFHLMREL
ENGRIARLMFKLSVVNERGDSHNWSETGERLLLKLFRDYVFHQVDADGKA
RLDTNHYLNCLSKLDASSEEQILLTSRDNATVFVVSYRSIRQMLDRAYGE
LGK
3D structure
PDB4czy An Asymmetric Pan3 Dimer Recruits a Single Pan2 Exonuclease to Mediate Mrna Deadenylation and Decay.
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP B D271 N277 T279 M287 A300 R302 F353 H354 S357 E358 T359 K413 I415 D38 N44 T46 M54 A67 R69 F120 H121 S124 E125 T126 K174 I176
Gene Ontology
Biological Process
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006397 mRNA processing
Cellular Component
GO:0031251 PAN complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:4czy, PDBe:4czy, PDBj:4czy
PDBsum4czy
PubMed24880343
UniProtQ7SDP4|PAN3_NEUCR PAN2-PAN3 deadenylation complex subunit pan3 (Gene Name=par-2)

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