Structure of PDB 4cmd Chain B

Receptor sequence
>4cmdB (length=322) [Search protein sequence]
MATMDKVFAGYAERQAVLEASKNPLAKGVAWIQGELVPLHEARIPLLDQG
FMHSDLTYDVPSVWDGRFFRLEDHLNRLEASCKKMRLRMPLPREEVIKTL
VDMVAKSGIRDAFVELIVTRGLTGVRGAKPEELLNNNLYMFIQPYVWVMD
PDVQYTGGRAIVARTVRRVPPGSIDPTIKNLQWGDLVRGLFEANDRGATY
PFLTDGDANLTEGSGFNVVLIKDGVLYTPDRGVLQGITRKSVIDAARSCG
YEIRVEHVPIEATYQADEILMCTTAGGIMPITTLDDKPVKDGKVGPITKA
IWDRYWAMHWEDEFSFKINYLE
3D structure
PDB4cmd The Substrate Specificity, Enantioselectivity and Structure of the (R)-Selective Amine:Pyruvate Transaminase from Nectria Haematococca.
ChainB
Resolution1.68 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y58 V60 K179 E212 L234
Catalytic site (residue number reindexed from 1) Y58 V60 K179 E212 L234
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B R77 K179 E212 G215 F216 L234 G236 I237 T238 T274 R77 K179 E212 G215 F216 L234 G236 I237 T238 T274
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
Biological Process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:4cmd, PDBe:4cmd, PDBj:4cmd
PDBsum4cmd
PubMed24618038
UniProtC7YVL8

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