Structure of PDB 4cb0 Chain B

Receptor sequence
>4cb0B (length=220) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
AGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGE
SKELERIETEAQRLDSMINDLLVSETIKANQLWSEVLDNAAFEAEQMGKS
LTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGIT
ITVDDDGPGVSPEDREQIFRPFYRTDEARDRTGLGLAIVETAIQQHRGWV
KAEDSPLGGLRLVIWLPLYK
3D structure
PDB4cb0 Segmental Helical Motions and Dynamical Asymmetry Modulate Histidine Kinase Autophosphorylation.
ChainB
Resolution3.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.13.3: histidine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B N360 Y364 I399 R405 T406 T417 G418 G420 L421 L445 N129 Y133 I168 R174 T175 T182 G183 G185 L186 L210
Gene Ontology
Molecular Function
GO:0000155 phosphorelay sensor kinase activity
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0007165 signal transduction
GO:0016310 phosphorylation
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4cb0, PDBe:4cb0, PDBj:4cb0
PDBsum4cb0
PubMed24492262
UniProtP0AE82|CPXA_ECOLI Sensor histidine kinase CpxA (Gene Name=cpxA)

[Back to BioLiP]