Structure of PDB 4c9d Chain B

Receptor sequence
>4c9dB (length=260) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
ASMPQAVVLELVGEKPPLYPARYAHGLFFALLSRVSPELAQKLHEAPRKP
FTLAPLPRTLKGTLRLRLTTLDDGLFAPFLRALLEAAPDGLPLGDSSYRL
ARVLATREGHPLAGATSWEELKEAPKREKATFRFLTPTVFATSKPGGRTR
YTPLPDPRLIAGSLLDKWQAHSPFPYNPKEEAALRELFELDLEVAGFRNL
RFHRVQAGKGFFPGFTGEATLRLWSQSLEAQEALGRLHALAFFSGVGAKT
PYGMGLAVPL
3D structure
PDB4c9d Evolution of CRISPR RNA recognition and processing by Cas6 endonucleases.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B E197 W228 E193 W224 PDBbind-CN: Kd=3.9nM
BS02 rna B H23 H42 P45 K47 F144 A145 T146 S147 K148 P149 T153 Y155 R162 L163 R208 K213 G214 G251 A252 K253 P255 Y256 H25 H44 P47 K49 F140 A141 T142 S143 K144 P145 T149 Y151 R158 L159 R204 K209 G210 G247 A248 K249 P251 Y252 PDBbind-CN: Kd=3.9nM
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:4c9d, PDBe:4c9d, PDBj:4c9d
PDBsum4c9d
PubMed24150936
UniProtQ53VU8

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