Structure of PDB 4c8z Chain B

Receptor sequence
>4c8zB (length=231) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MVLAALVLVLEGEGLPEPLGLRGFFYGLLREVAENPFALGFGGREGAAWA
RVSLLVEGLYARLAPRLYALEGEEVRLGPPFRVRAVLQEGHPWAGVSTYP
RLFQGPPSRDLALRFASPTFFRRKGVHYPVPEPRLVLESLLRRLEAFGPL
KAPEGVREALLERTTVRSLEGRTLPARTEVDTAGFVGRVVYHLPRATEEE
ALWLSALGRFAFYSGVGAKTSLGYGRARAES
3D structure
PDB4c8z Evolution of Crispr RNA Recognition and Processing by Cas6 Endonucleases.
ChainB
Resolution2.503 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B R174 H199 R202 R167 H192 R195 PDBbind-CN: Kd=90pM
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:4c8z, PDBe:4c8z, PDBj:4c8z
PDBsum4c8z
PubMed24150936
UniProtQ5SM65

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