Structure of PDB 4bxo Chain B

Receptor sequence
>4bxoB (length=196) Species: 9606 (Homo sapiens) [Search protein sequence]
VHVPLGHIVANEKWRGSQLAEEMQGKIKLIFEDGLTPDFYLSNRCCILYV
TEADLVAGNGYRKRLVRVRNSNNLKGIVVVEKTRMSEQYFPALQKFTVLD
LGMVLLPVASQMEASCLVIQLVQEQTKEPSKNPLLLSEPSLLRTVQQIPG
VGKVKAPLLLQKFPSIQQLSNASIGELEQVVGQAVAQQIHAFFTQP
3D structure
PDB4bxo Architecture and DNA Recognition Elements of the Fanconi Anemia Fancm-Faap24 Complex.
ChainB
Resolution2.15 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K173 V199 G200 V203 K155 V181 G182 V185 PDBbind-CN: Kd=1.85uM
BS02 dna B G168 G170 V172 K173 G150 G152 V154 K155 PDBbind-CN: Kd=1.85uM
BS03 CA B Q164 V169 Q146 V151
BS04 CA B E196 V199 E178 V181
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0005515 protein binding
Biological Process
GO:0006281 DNA repair
GO:0036297 interstrand cross-link repair
Cellular Component
GO:0000785 chromatin
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0043231 intracellular membrane-bounded organelle
GO:0043240 Fanconi anaemia nuclear complex
GO:0071821 FANCM-MHF complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4bxo, PDBe:4bxo, PDBj:4bxo
PDBsum4bxo
PubMed23932590
UniProtQ9BTP7|FAP24_HUMAN Fanconi anemia core complex-associated protein 24 (Gene Name=FAAP24)

[Back to BioLiP]