Structure of PDB 4bwp Chain B

Receptor sequence
>4bwpB (length=372) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
PLEVENYHALYPLEPPAQPLHAKLTFPATTYRATHNTTGYKYCLRRIHGF
RLQSTKCMTLVEMWKKLQHTNVVQLREVFTTKAFGDNSLVLVYDYHPGSQ
TLLAKYFTPTSNGPLLPEATIWSIIMQLTAGLKAIHHAGLACKVLDPTKI
IVTGKRVRFSSCCISDITQFDPNASNPLALVNMHQQDDLTALGRLVLALA
CRCLQSVQRDNVQSSIDMVTRNYSTDLRNFIVYLFTTNNRRSVTDLMPMI
GARFYTQLDALQSKIDMQEDELAKEMENGRLYRILVKLNSINERPGDRYM
LKLFRDYLFHSVTEDGRPWLDHAHIVQCLNKLDAGSIERVQLMSRDEQSV
LIVSYAELKNCLENAFSELMSS
3D structure
PDB4bwp Structure of the Pan3 Pseudokinase Reveals the Basis for Interactions with the Pan2 Deadenylase and the Gw182 Proteins
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AN2 B A395 Q396 T408 C421 R423 Y473 H474 S477 T479 A17 Q18 T30 C43 R45 Y95 H96 S99 T101
Gene Ontology
Biological Process
GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening
GO:0006397 mRNA processing
Cellular Component
GO:0031251 PAN complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bwp, PDBe:4bwp, PDBj:4bwp
PDBsum4bwp
PubMed23932717
UniProtQ95RR8|PAN3_DROME PAN2-PAN3 deadenylation complex subunit PAN3 (Gene Name=PAN3)

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