Structure of PDB 4bwe Chain B

Receptor sequence
>4bweB (length=422) Species: 9606 (Homo sapiens) [Search protein sequence]
KSRSCGEVRQIYGAKGFSLSDVPQAEISGEHLRICPQGYTCCTSEMEENL
ANRSHAELETALRDSSRVLQAMLATQLRSFDDHFQHLLNDSERTLQATFP
GAFGELYTQNARAFRDLYSELRLYYRGANLHLEETLAEFWARLLERLFKQ
LHPQLLLPDDYLDCLGKQAEALRPFGEAPRELRLRATRAFVAARSFVQGL
GVASDVVRKVAQVPLGPECSRAVMKLVYCAHCLGVPGARPCPDYCRNVLK
GCLANQADLDAEWRNLLDSMVLITDKFWGTSGVESVIGSVHTWLAEAINA
LQDNRDTLTAKVIQGCGNPKVNPSGTLEKLVSEAKAQLRDVQDFWISLPG
TLCSEKMADRCWNGMARGRYLPEVMGDGLANQINNPEVEVDITKPDMTIR
QQIMQLKIMTNRLRSAYNGNDV
3D structure
PDB4bwe Improvements in the order, isotropy and electron density of glypican-1 crystals by controlled dehydration.
ChainB
Resolution2.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B I437 E443 I383 E389
BS02 CA B D388 D391 D340 D343
Gene Ontology
Biological Process
GO:0009966 regulation of signal transduction
Cellular Component
GO:0005886 plasma membrane
GO:0062023 collagen-containing extracellular matrix

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Biological Process
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Cellular Component
External links
PDB RCSB:4bwe, PDBe:4bwe, PDBj:4bwe
PDBsum4bwe
PubMed24311593
UniProtP35052|GPC1_HUMAN Glypican-1 (Gene Name=GPC1)

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