Structure of PDB 4brq Chain B

Receptor sequence
>4brqB (length=359) Species: 446 (Legionella pneumophila) [Search protein sequence]
NPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPGFA
SIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYDEL
DYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGVMD
MGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEMSH
QFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQPLL
ALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQWDI
LNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDWTI
GVVLHRALE
3D structure
PDB4brq Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
ChainB
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.5: apyrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B T53 K80 Q231 G299 N302 L303 Y346 Y350 T17 K44 Q195 G263 N266 L267 Y310 Y314
BS02 PO4 B S52 T53 R56 G188 G189 S16 T17 R20 G152 G153
BS03 PO4 B T118 A119 E159 G188 A190 S191 T82 A83 E123 G152 A154 S155
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4brq, PDBe:4brq, PDBj:4brq
PDBsum4brq
PubMed23830739
UniProtQ5ZUA2

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