Structure of PDB 4brg Chain B

Receptor sequence
>4brgB (length=361) Species: 446 (Legionella pneumophila) [Search protein sequence]
DTNPCEKHSCIAVIDAGSTGSRLHIYSYDTDDTNTPIHIEEIWNKKIKPG
FASIQPNSVTIDAYLTMLLADAPIHNIPVYFYATAGMRLLPQSQQKKYYD
ELDYWFRQQSQWQLVEAKTITGNDEALFDWLAVNYKLDTLKSVQNKSVGV
MDMGGASVQIVFPMPKNAEISKHNQVELNIYGQNINLYVHSFLGLGQTEM
SHQFLNSPSCFANDYPLPDGESGQGNAPSCKEEVTSLMNSVHKVNQQIQP
LLALNPVNEWYSIGGISNLASSQLFHFENSELTNQSLLQQGDNQICHQQW
DILNGQYPDDEYLYQYCLLSSYYYALMVDGYGINPNQTIHYIPPEQNLDW
TIGVVLHRALE
3D structure
PDB4brg Crystallographic Snapshots Along the Reaction Pathway of Nucleoside Triphosphate Diphosphohydrolases
ChainB
Resolution1.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.5: apyrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B G51 S52 T53 R56 G189 A190 Q231 G299 N302 Y346 Y350 G17 S18 T19 R22 G155 A156 Q197 G265 N268 Y312 Y316
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:4brg, PDBe:4brg, PDBj:4brg
PDBsum4brg
PubMed23830739
UniProtQ5ZUA2

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