Structure of PDB 4bp3 Chain B

Receptor sequence
>4bp3B (length=280) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDG
VIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSV
ENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTY
DVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTI
KNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLES
KEFADLKYYNYENHSAAFKLPAFLLKEIEN
3D structure
PDB4bp3 Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4MN B Y102 D199 Q229 Y264 I269 Y62 D159 Q189 Y224 I229
BS02 S4M B Q93 Y102 H103 G124 D127 E147 I148 V152 D178 A179 D196 S198 P203 A204 L207 Q53 Y62 H63 G84 D87 E107 I108 V112 D138 A139 D156 S158 P163 A164 L167
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4bp3, PDBe:4bp3, PDBj:4bp3
PDBsum4bp3
PubMed25760598
UniProtQ8II73

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