Structure of PDB 4bp1 Chain B

Receptor sequence
>4bp1B (length=280) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
KKWFSEFSIMWPGQAFSLKIKKILYETKSKYQNVLVFESTTYGKVLVLDG
VIQLTEKDEFAYHEMMTHVPMTVSKEPKNVLVVGGGDGGIIRELCKYKSV
ENIDICEIDETVIEVSKIYFKNISCGYEDKRVNVFIEDASKFLENVTNTY
DVIIVDSSDPIGPAETLFNQNFYEKIYNALKPNGYCVAQCESLWIHVGTI
KNMIGYAKKLFKKVEYANISIPTYPCGCIGILCCSKTDTGLTKPNKKLES
KEFADLKYYNYENHSAAFKLPAFLLKEIEN
3D structure
PDB4bp1 Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design
ChainB
Resolution2.17 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.16: spermidine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MTA B Q72 Q93 G124 G125 D127 E147 I148 V152 D178 A179 D196 S198 P203 A204 L207 Q32 Q53 G84 G85 D87 E107 I108 V112 D138 A139 D156 S158 P163 A164 L167
BS02 PUT B Q93 D196 S197 D199 Y264 Q53 D156 S157 D159 Y224
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4bp1, PDBe:4bp1, PDBj:4bp1
PDBsum4bp1
PubMed25760598
UniProtQ8II73

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