Structure of PDB 4bld Chain B

Receptor sequence
>4bldB (length=717) Species: 9606,83333 [Search protein sequence]
EGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAAT
GDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKL
IAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQE
PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKH
MNADTDYSIAEHAFNHGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQ
PSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVA
LKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASG
RQTVDAALAAAQTNAAAPGLHAIYGECRRLYPDQPNPLQVTAIVKYDSFG
PDPLDYVSMYRNVGSPSANIPEHWHYISFGLSDLYGDNRVHEFTGTDGPS
GFGFELTFRLKRETGESAPPTWPAELMQGLARYVFQSENTFCSGDHVSWH
SPLDNSESRIQHMLLTEDPQMQPVQTPFGVVTFLQIVGVCTEELHSAQQW
NGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGS
NLSGVSAKCAWDSVHLKFNQESGALIPLCLRGRLLHGRHFTYKSITGDMA
ITFTGVEGAFATEEHAHGPWLQILLTEEFVEKMLEDLEDALPKEYSWPEK
KLKVSILPDVEHHHHHH
3D structure
PDB4bld Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation
ChainB
Resolution2.802 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y487 F495 D499 H500 V501 S502 W503 L606 S607 V609 S610 E641 Y483 F491 D495 H496 V497 S498 W499 L602 S603 V605 S606 E621
BS02 GLC B D15 K16 E112 W231 D11 K12 E108 W227
BS03 GLC B W63 D66 R67 E154 Y156 W341 W59 D62 R63 E150 Y152 W337
BS04 ZN B H216 E222 H212 E218
BS05 ZN B H751 H753 H715 H717
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0015144 carbohydrate transmembrane transporter activity
GO:1901982 maltose binding
Biological Process
GO:0006974 DNA damage response
GO:0008643 carbohydrate transport
GO:0015768 maltose transport
GO:0034219 carbohydrate transmembrane transport
GO:0034289 detection of maltose stimulus
GO:0042956 maltodextrin transmembrane transport
GO:0055085 transmembrane transport
GO:0060326 cell chemotaxis
Cellular Component
GO:0016020 membrane
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space
GO:0043190 ATP-binding cassette (ABC) transporter complex
GO:0055052 ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
GO:1990060 maltose transport complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bld, PDBe:4bld, PDBj:4bld
PDBsum4bld
PubMed24311597
UniProtP0AEX9|MALE_ECOLI Maltose/maltodextrin-binding periplasmic protein (Gene Name=malE);
Q9UMX1|SUFU_HUMAN Suppressor of fused homolog (Gene Name=SUFU)

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