Structure of PDB 4bc2 Chain B

Receptor sequence
>4bc2B (length=527) Species: 9606 (Homo sapiens) [Search protein sequence]
PRRCCLGWDFSTQQVKVVAVDAELNVFYEESVHFDRDLPEFGTQGGVHVH
KDGLTVTSPVLMWVQALDIILEKMKASGFDFSQVLALSGAGQQHGSIYWK
AGAQQALTSLSPDLRLHQQLQDCFSISDCPVWMDSSTTAQCRQLEAAVGG
AQALSCLTGSRAYERFTGNQIAKIYQQNPEAYSHTERISLVSSFAASLFL
GSYSPIDYSDGSGMNLLQIQDKVWSQACLGACAPHLEEKLSPPVPSCSVV
GAISSYYVQRYGFPPGCKVVAFTGDNPASLAGMRLEEGDIAVSLGTSDTL
FLWLQEPMPALEGHIFCNPVDSQHYMALLCFKNGSLMREKIRNESVSRSW
SDFSKALQSTEMGNGGNLGFYFDVMEITPEIIGRHRFNTENHKVAAFPGD
VEVRALIEGQFMAKRIHAEGLGYRVMSKTKILATGGASHNREILQVLADV
FDAPVYVIDTANSACVGSAYRAFHGLAGGTDVPFSEVVKLAPNPRLAATP
SPGASQVYEALLPQYAKLEQRILSQTR
3D structure
PDB4bc2 Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism
ChainB
Resolution1.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.17: xylulokinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B W355 G441 A442 N445 W350 G436 A437 N440
BS02 XUL B Q97 Q98 H99 W137 R170 D280 N281 Q92 Q93 H94 W132 R165 D275 N276
Gene Ontology
Molecular Function
GO:0004856 D-xylulokinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005997 xylulose metabolic process
GO:0005998 xylulose catabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0016310 phosphorylation
GO:0019640 D-glucuronate catabolic process to D-xylulose 5-phosphate
GO:0042732 D-xylose metabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4bc2, PDBe:4bc2, PDBj:4bc2
PDBsum4bc2
PubMed23179721
UniProtO75191|XYLB_HUMAN Xylulose kinase (Gene Name=XYLB)

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