Structure of PDB 4b7v Chain B

Receptor sequence
>4b7vB (length=410) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
RRVVITGMGMLSPLGLDVPSSWEGILAGRSGIAPIEHMDLSAYSTRFGGS
VKGFNVEEYLSAKEARKLDLFIQYGLAASFQAVRDSGLEVTDANRERIGV
SMGSGIGGLTNIENNCRSLFEQGPRRISPFFVPGSIINMVSGFLSIHLGL
QGPNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSEMAACGLGLGGF
GAARALSTRNDEPTRASRPWDRDRDGFVLSDGSGALVLEELEHARARGAR
IYAELVGFGMSGDAFHMTAPPEDGAGAARCMKNALRDAGLDPRQVDYINA
HGTSTPAGDIAEIAAVKSVFGEHAHALSMSSTKSMTGHLLGAAGAVEAIF
SVLALRDQVAPPTINLDNPDEGCDLDLVAHEAKPRKIDVALSNSFGFGGT
NGTLVFRRFA
3D structure
PDB4b7v Structures of Pseudomonas Aeruginosa Beta-Keto-Acyl-(Acyl-Carrier-Protein) Synthase II (Fabf) and a C164Q Mutant Provide Templates for Antibacterial Drug Discovery and Identify a Buried Potassium Ion and a Ligand-Binding Site that is an Artefact of the Crystal Form
ChainB
Resolution1.73 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) C164 H304 E315 K336 H341 F398 F400
Catalytic site (residue number reindexed from 1) C161 H301 E312 K333 H338 F395 F397
Enzyme Commision number 2.3.1.179: beta-ketoacyl-[acyl-carrier-protein] synthase II.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 K B N302 A303 H304 E350 S395 N396 N299 A300 H301 E347 S392 N393
Gene Ontology
Molecular Function
GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
Biological Process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4b7v, PDBe:4b7v, PDBj:4b7v
PDBsum4b7v
PubMed26249693
UniProtG3XDA2

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