Structure of PDB 4b52 Chain B

Receptor sequence

>4b52B (length=304) Species: 1406 (Paenibacillus polymyxa) [Search protein sequence]

ATGTGKGVLGDTKSFTTTASGSSYQLKDTTRGNGVVTYTASNRQSIPGTI
LTDADNVWNDPAGVDAHTYAAKTYDYYKAKFGRNSIDGRGLQLRSTVHYG
SRYNNAFWNGSQMTYGDGDGSTFIAFSGDPDVVGHELTHGVTEYTSNLEY
YGESGALNEAFSDVIGNDIQRKNWLVGDDIYTPNIAGDALRSMSNPTLYD
QPDHYSNLYTGSSDNGGVHTNSGIINKAYYLLAQGGTFHGVTVNGIGRDA
AVQIYYSAFTNYLTSSSDFSNARAAVIQAAKDQYGANSAEATAAAKSFDA
VGVN

3D structure

PDB

4b52 Structure of Gentlyase, the Neutral Metalloprotease of Paenibacillus Polymyxa

Chain

Resolution

1.76 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	H135 E136 H139 Y150 E159 D214 H219
Catalytic site (residue number reindexed from 1)	H135 E136 H139 Y150 E159 D214 H219
Enzyme Commision number	3.4.24.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	ZN	B	H135 H139 E159	H135 H139 E159
BS02	CA	B	D129 D131 Q170 D178 D179	D129 D131 Q170 D178 D179
BS03	CA	B	D53 D55 V57	D53 D55 V57
BS04	CA	B	Y181 T182 I185 D188	Y181 T182 I185 D188
BS05	RDF	B	N104 N105 A106 F123 F126 V132 H135 E136 H139 E159 L190 R191 H219	N104 N105 A106 F123 F126 V132 H135 E136 H139 E159 L190 R191 H219

Gene Ontology

	Molecular Function
GO:0004222	metalloendopeptidase activity

	Biological Process
GO:0006508	proteolysis

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:4b52, PDBe:4b52, PDBj:4b52
PDBsum	4b52
PubMed	23275160
UniProt	E3E6L0

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