Structure of PDB 4b20 Chain B

Receptor sequence
>4b20B (length=223) Species: 2336 (Thermotoga maritima) [Search protein sequence]
MDYRQLHRWDLPPEEAIKVQNELRKKIKLTPYEGEPEYVAGVDLSFPGKE
EGLAVIVVLEYPSFKILEVVSERGEITFPYIPGLLAFREGPLFLKAWEKL
RTKPDVVVFDGQGLAHPRKLGIASHMGLFIEIPTIGVAKSRLYGTFKMPE
DKRCSWSYLYDGEEIIGCVIRTKEGSAPIFVSPGHLMDVESSKRLIKAFT
LPGRRIPEPTRLAHIYTQRLKKG
3D structure
PDB4b20 Structural Basis of DNA Loop Recognition by Endonuclease V.
ChainB
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.7: deoxyribonuclease V.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B L220 K222 G223 L220 K222 G223 PDBbind-CN: Kd=0.11uM
BS02 dna B Y80 G83 L85 D110 Q112 H116 G121 I122 A138 K139 S140 R141 L142 Y80 G83 L85 D110 Q112 H116 G121 I122 A138 K139 S140 R141 L142 PDBbind-CN: Kd=0.11uM
BS03 dna B F46 K221 F46 K221 PDBbind-CN: Kd=0.11uM
BS04 MG B D43 D110 D43 D110
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003727 single-stranded RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0043737 deoxyribonuclease V activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:4b20, PDBe:4b20, PDBj:4b20
PDBsum4b20
PubMed23313664
UniProtQ9X2H9|NFI_THEMA Endonuclease V (Gene Name=nfi)

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