Structure of PDB 4axg Chain B

Receptor sequence
>4axgB (length=167) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
KHPLMNVWTLWYLENMQNEITSFDTVEDFWSLYNHIKPPSEIKLGSDYSL
FKKNIRPMWEDAANKQGGRWVITLNKSSKTDLDNLWLDVLLCLIGEAFDH
SDQICGAVINIRGKSNKISIWTADGNNEEAALEIGHKLRDALRLGRNNSL
QYQLHKDTMNVKSIYTL
3D structure
PDB4axg Crystal Structure of a Minimal Eif4E-Cup Complex Revelas a General Mechanism of Eif4E Regulation in Translational Repression
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H70 P71 V102 W106 N110 L167 G171 H2 P3 V26 W30 N34 L91 G95
Gene Ontology
Molecular Function
GO:0000339 RNA cap binding
GO:0000340 RNA 7-methylguanosine cap binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0031370 eukaryotic initiation factor 4G binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation
GO:0006417 regulation of translation
GO:0016070 RNA metabolic process
Cellular Component
GO:0000932 P-body
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016281 eukaryotic translation initiation factor 4F complex
GO:0016604 nuclear body
GO:0031594 neuromuscular junction
GO:0036464 cytoplasmic ribonucleoprotein granule
GO:0071598 neuronal ribonucleoprotein granule
GO:0097482 muscle cell postsynaptic specialization

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Cellular Component
External links
PDB RCSB:4axg, PDBe:4axg, PDBj:4axg
PDBsum4axg
PubMed22832024
UniProtP48598|IF4E_DROME Eukaryotic translation initiation factor 4E1 (Gene Name=eIF4E1)

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