Structure of PDB 4ati Chain B

Receptor sequence
>4atiB (length=71) Species: 10090 (Mus musculus) [Search protein sequence]
RQKKDNHNLIERRRRFNINDRIKELGTLIPKSDPDMRWNKGTILKASVDY
IRKLQREQQRAKDLENRQKKL
3D structure
PDB4ati Restricted Leucine Zipper Dimerization and Specificity of DNA Recognition of the Melanocyte Master Regulator Mitf
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B H209 I212 E213 R216 H7 I10 E11 R14 PDBbind-CN: Kd=2.5nM
BS02 dna B K206 H209 N210 E213 R214 R217 N242 K243 K4 H7 N8 E11 R12 R15 N39 K40 PDBbind-CN: Kd=2.5nM
Gene Ontology
Molecular Function
GO:0046983 protein dimerization activity

View graph for
Molecular Function
External links
PDB RCSB:4ati, PDBe:4ati, PDBj:4ati
PDBsum4ati
PubMed23207919
UniProtQ08874|MITF_MOUSE Microphthalmia-associated transcription factor (Gene Name=Mitf)

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