Structure of PDB 4ar9 Chain B

Receptor sequence
>4ar9B (length=392) Species: 1513 (Clostridium tetani) [Search protein sequence]
TDINKLIEEGKKHYLPKTYTFDNGKIIIKAGDKVEESKIQKLYWASKEVK
SQFHRIIGNDKPLEVGNADDILTIVIYNNPEEYKLNKTLYGYSVDNGGIY
IEGIGTFFTYERTPQESIYSLEELFRHEFTHYLQGRYLIPGLFNKGDFYK
GNNGRITWFEEGSAEFFAGSTRTSVLPRKSMVGGLSKNPKERFNADKLLH
SKYSDGWDFYKYGYAFSDYMYNNNKKLFSDLVSTMKNNDVKGYEALIEES
SKDSKINKDYEYHMENLVNNYDNYTIPLVSDDYMKQYDNKSLHEIKSDIE
KAMDVKNSQITKESSQYFDTYNLKATYTLSSNKGEISNWNYMNNKINEAL
NKLDNLSWGGYKTVTAYFSNPRLNSNNEVVYDIVFHGLLSHN
3D structure
PDB4ar9 Structural Basis for Activity Regulation and Substrate Preference of Clostridial Collagenases G, H, and T.
ChainB
Resolution1.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.3: microbial collagenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B H465 H469 E499 H127 H131 E161
BS02 CA B E440 G473 I477 G479 E102 G135 I139 G141
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4ar9, PDBe:4ar9, PDBj:4ar9
PDBsum4ar9
PubMed23703618
UniProtQ899Y1|COLT_CLOTE Collagenase ColT (Gene Name=colT)

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