Structure of PDB 4aqe Chain B

Receptor sequence
>4aqeB (length=238) Species: 10090 (Mus musculus) [Search protein sequence]
MQYDDDWQYEDCKLARGGPPATIVAIDEESRNGTILVDNMLIKGTAGGPD
PTIELSLKDNVDYWVLLDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQC
VNKKVGTVIYHEVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGF
SGDNGATDIDDGPNGQIEYVIQYNPEDPTSNDTFEIPLMLTGNVVLRKRL
NYEDKTRYYVIIQANDRAQNLNERRTTTTTLTVDLEHH
3D structure
PDB4aqe Structure of a Force-Conveying Cadherin Bond Essential for Inner-Ear Mechanotransduction
ChainB
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B E27 E28 D83 D85 D121 E28 E29 D84 D86 D122
BS02 CA B E27 D85 D118 R119 D121 D159 E28 D86 D119 R120 D122 D160
BS03 CA B N120 N122 D157 D159 N163 D215 N121 N123 D158 D160 N164 D216
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007605 sensory perception of sound
GO:0048839 inner ear development
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0032420 stereocilium

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Cellular Component
External links
PDB RCSB:4aqe, PDBe:4aqe, PDBj:4aqe
PDBsum4aqe
PubMed23135401
UniProtQ99PJ1|PCD15_MOUSE Protocadherin-15 (Gene Name=Pcdh15)

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