Structure of PDB 4ags Chain B

Receptor sequence
>4agsB (length=440) Species: 5671 (Leishmania infantum) [Search protein sequence]
ALKLYVSATCPFCHRVEIVAREKQVSYDRVAVGLREEMPQWYKQINPRET
VPTLEVGNADKRFMFESMLIAQYLDNSGAPAGALMGSSAAQRHQIEFFLA
QVGDFIGAAHGLLRDPLSGEKRKAMDDNAAYVDGLLAANQTTGPYYCDGE
FTMADVALVPFLVRLKPALMYYAGYDVFCKAPRMKALWAAAAQRASVRET
SPTAAQCIENYRHLVPESAPMMGANGGHVLYSNLFCPFVDRARLASELRK
FQMHIVEVPLHPQPEWYKYINPRDTVPALFTPSGEAVHESQLIVQYIDCV
ATKGSALVPRGDAEKEYEVGFFVENAGYFVGGLMSWIIRGGEDAKAELQW
AAGELEQQLAKHPFGEGPFFGGKRMNAGDVAILPFLVRAKAFMPEFSGGY
DLFAHFPLLNGLAEAGMATPEAKSVFRTLEEYKEHIRKRQ
3D structure
PDB4ags Leishmania Tdr1 Structure, a Unique Trimeric Glutathione Transferase Capable of Deglutathionylation and Antimonial Prodrug Activation.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH B C240 F242 H265 Q267 T279 V280 E293 S294 C236 F238 H261 Q263 T275 V276 E289 S290
BS02 GSH B C14 F16 L38 R39 T54 V55 E70 S71 C10 F12 L34 R35 T50 V51 E66 S67
Gene Ontology
Molecular Function
GO:0042802 identical protein binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:4ags, PDBe:4ags, PDBj:4ags
PDBsum4ags
PubMed22753509
UniProtA4I8P2

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