Structure of PDB 4aec Chain B

Receptor sequence
>4aecB (length=319) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
GLNIADNVSQLIGKTPMVYLNSIAKGCVANIAAKLEIMEPCCSVKDRIGY
SMVTDAEQKGFISPGKSVLVEPTSGNTGIGLAFIAASRGYRLILTMPASM
SMERRVLLKAFGAELVLTDPAKGMTGAVQKAEEILKNTPDAYMLQQFDNP
ANPKIHYETTGPEIWDDTKGKVDIFVAGIGTGGTITGVGRFIKEKNPKTQ
VIGVEPTESDILSGGKPGPHKIQGIGAGFIPKNLDQKIMDEVIAISSEEA
IETAKQLALKEGLMVGISSGAAAAAAIKVAKRPENAGKLIAVVFPSFGER
YLSTPLFQSIREEVEKMQP
3D structure
PDB4aec Allosterically Gated Enzyme Dynamics in the Cysteine Synthase Complex Regulate Cysteine Biosynthesis in Arabidopsis Thaliana.
ChainB
Resolution2.4 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K154 S377
Catalytic site (residue number reindexed from 1) K45 S268
Enzyme Commision number 2.5.1.47: cysteine synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B K154 N185 I288 G289 T290 G291 T293 G333 S377 P404 S405 K45 N76 I179 G180 T181 G182 T184 G224 S268 P295 S296
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0042802 identical protein binding
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0009567 double fertilization forming a zygote and endosperm
GO:0009860 pollen tube growth
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4aec, PDBe:4aec, PDBj:4aec
PDBsum4aec
PubMed22325778
UniProtQ43725|CYSKM_ARATH Cysteine synthase, mitochondrial (Gene Name=OASC)

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