Structure of PDB 4add Chain B

Receptor sequence
>4addB (length=400) Species: 511693 (Escherichia coli BL21) [Search protein sequence]
QPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNA
LGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQP
AYSQDFAPLPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPAS
NAFLQGLRELCNRHNALLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAK
ALGGGFPVGALLATEECARVMTVGTHGTTYGGNPLASAVAGKVLELINTP
EMLNGVKQRHDWFVERLNTINHRYGLFSEVRGLGLLIGCVLNADYAGQAK
QISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAAACEHFVS
3D structure
PDB4add Determination of the Structure of the Catabolic N-Succinylornithine Transaminase (Astc) from Escherichia Coli.
ChainB
Resolution2.45 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F138 E190 D223 Q226 K252 T281 R374
Catalytic site (residue number reindexed from 1) F136 E188 D221 Q224 K250 T279 R372
Enzyme Commision number 2.6.1.81: succinylornithine transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SUO B G77 G279 G75 G277
BS02 PLP B G105 A106 F138 H139 E190 D223 V225 G103 A104 F136 H137 E188 D221 V223
BS03 SUO B Y18 F138 R141 E195 K252 Y16 F136 R139 E193 K250
Gene Ontology
Molecular Function
GO:0003992 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO:0008483 transaminase activity
GO:0030170 pyridoxal phosphate binding
GO:0042802 identical protein binding
GO:0043825 succinylornithine transaminase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006525 arginine metabolic process
GO:0006526 L-arginine biosynthetic process
GO:0006527 arginine catabolic process
GO:0006593 ornithine catabolic process
GO:0019544 arginine catabolic process to glutamate
GO:0019545 arginine catabolic process to succinate
GO:0042450 arginine biosynthetic process via ornithine

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Molecular Function
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Biological Process
External links
PDB RCSB:4add, PDBe:4add, PDBj:4add
PDBsum4add
PubMed23484010
UniProtP77581|ASTC_ECOLI Succinylornithine transaminase (Gene Name=astC)

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