Structure of PDB 4a59 Chain B

Receptor sequence
>4a59B (length=593) Species: 5811 (Toxoplasma gondii) [Search protein sequence]
ADTEKRINVGKKHLQTLRNLETRCHDSLQALVVIDAGSSSTRTNVFLAKT
RSCPNKGRSIDPDSIQLIGAGKRFAGLRVVLEEWLDTYAGKDWESRPVDA
RLLFQYVPQMHEGAKKLMQLLEEDTVAILDSQLNEKQKVQVKALGIPVML
CSTAGVRDFHEWYRDALFVLLRHLINNPSPAHGYKFFTNPFWTRPITGAE
EGLFAFITLNHLSRRLGEDPARCMIDEYGVKQCRNDLAGVVEVGGASAQI
VFPLQEGTVLPSSVRAVNLQRERLLPERYPSADVVSVSFMQLGMASSAGL
FLKELCSNDEFLQGGICSNPCLFKGFQQSCSAGEVEVRPDGSASVNEDVR
KNRLKPLATYCSVNNPEISFKVTNEMQCRENSIDPTKPLAERMKIENCSI
IKGTGNFDKCVSQVESILVAPKLPLPANIEAASSGFESVDQVFRFASSTA
PMIVTGGGMLAAINTLKDHRLLRSDFSGDVEELAEAAREFCSSEVIIRTD
GPVIQLPNARGEQKLNSLNFDLCKTMALTVSLLRHMAAGENQPSFIKWEK
SIAGPDGKPLADLGWQVGVILHHVLFTEEWGRNAYEAGYSHNL
3D structure
PDB4a59 Structural Insight Into the Activation Mechanism of Toxoplasma Gondii Nucleoside Triphosphate Diphosphohydrolases by Disulfide Reduction.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.15: nucleoside-triphosphate phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B M329 G491 G492 G493 A496 L553 M294 G456 G457 G458 A461 L518
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
Cellular Component
GO:0005576 extracellular region
GO:0020003 symbiont-containing vacuole

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Molecular Function
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Cellular Component
External links
PDB RCSB:4a59, PDBe:4a59, PDBj:4a59
PDBsum4a59
PubMed22130673
UniProtQ27893|NTP1_TOXGO Nucleoside-triphosphatase 1 (Gene Name=NTP3)

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