Structure of PDB 4a3q Chain B

Receptor sequence
>4a3qB (length=356) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
SDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYGLGSVKVA
RHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRV
ALTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTNTYQEVI
EIIQQYEQLVFEGVFTHFTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLM
DCQFCNAIRPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLPTT
IALLPIGYADGYLRIMQGSFVNVNGHQCEVIGRVCMDQTIVKVPDQVKAG
DSVILIDNHRESPQSVEVVAEKQHTINYEVLCNLSRRLPRIYHDGDQRFV
TNELLK
3D structure
PDB4a3q Structural Features and Kinetic Characterization of Alanine Racemase from Staphylococcus Aureus (Mu50)
ChainB
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K39 R138 H168 R219 C311 D313
Catalytic site (residue number reindexed from 1) K38 R137 H167 R209 C285 D287
Enzyme Commision number 5.1.1.1: alanine racemase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP B K39 Y43 H168 S204 R219 G221 I222 Y354 K38 Y42 H167 S194 R209 G211 I212 Y328
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008784 alanine racemase activity
GO:0016853 isomerase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0006522 alanine metabolic process
GO:0009252 peptidoglycan biosynthetic process
GO:0030632 D-alanine biosynthetic process
Cellular Component
GO:0005829 cytosol

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Biological Process
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Cellular Component
External links
PDB RCSB:4a3q, PDBe:4a3q, PDBj:4a3q
PDBsum4a3q
PubMed22194336
UniProtP63479|ALR1_STAAM Alanine racemase 1 (Gene Name=alr1)

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