Structure of PDB 4a1s Chain B

Receptor sequence

>4a1sB (length=342) Species: 7227 (Drosophila melanogaster) [Search protein sequence]

GSSMCLELALEGERLCNAGDCRAGVAFFQAAIQAGTEDLRTLSAIYSQLG
NAYFYLGDYNKAMQYHKHDLTLAKSMNDRLGEAKSSGNLGNTLKVMGRFD
EAAICCERHLTLARQLGDRLSEGRALYNLGNVYHAKGKHLGQRNPGKFGD
DVKEALTRAVEFYQENLKLMRDLGDRGAQGRACGNLGNTYYLLGDFQAAI
EHHQERLRIAREFGDRAAERRANSNLGNSHIFLGQFEDAAEHYKRTLALA
VELGEREVEAQSCYSLGNTYTLLHEFNTAIEYHNRHLAIAQELGDRIGEA
RACWSLGNAHSAIGGHERALKYAEQHLQLAAAAAAAAAAAAA

3D structure

PDB

4a1s Inscuteable and Numa Proteins Bind Competitively to Leu-Gly- Asn Repeat-Enriched Protein (Lgn) During Asymmetric Cell Divisions.

Chain

Resolution

2.1 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	L48 E51 R78 S85 Q86 N89 F92 Y93 D107 G119 N126 N129 R162 Y165 N166 K176 Q180 F186 R219 N223 N226 Y229 L230 R244 R258 R259 N263 F270 S303 N306 L310 W342 N346	L10 E13 R40 S47 Q48 N51 F54 Y55 D69 G81 N88 N91 R124 Y127 N128 K138 Q142 F148 R181 N185 N188 Y191 L192 R206 R220 R221 N225 F232 S265 N268 L272 W304 N308

External links

PDB	RCSB:4a1s, PDBe:4a1s, PDBj:4a1s
PDBsum	4a1s
PubMed	22171003
UniProt	Q9VB22

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