Structure of PDB 4a0l Chain B

Receptor sequence
>4a0lB (length=355) Species: 7955 (Danio rerio) [Search protein sequence]
GQTSILHYIYKSSLGQSIHAQLRQCLQEPFIRSLKSYKLHRTASPFDRRV
TSLEWHPTHPTTVAVGSKGGDIILWDYDVQNKTSFIQGMGPGDAITGMKF
NQFNTNQLFVSSIRGATTLRDFSGSVIQVFAKTDSWDYWYCCVDVSVSRQ
MLATGDSTGRLLLLGLDGHEIFKEKLHKAKVTHAEFNPRCDWLMATSSVD
ATVKLWDLRNIKDKNSYIAEMPHEKPVNAAYFNPTDSTKLLTTDQRNEIR
VYSSYDWSKPDQIIIHPHRQFQHLTPIKATWHPMYDLIVAGRYPDDQLLL
NDKRTIDIYDANSGGLVHQLRDPNAAGIISLNKFSPTGDVLASGMGFNIL
IWNRE
3D structure
PDB4a0l The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation.
ChainB
Resolution7.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B K168 P191 W236 W239 K280 P326 Q345 Q372 H373 K68 P91 W136 W139 K180 P226 Q245 Q272 H273
BS02 dna B R369 F371 Q372 H373 Y393 R404 G427 I428 F447 R269 F271 Q272 H273 Y293 R304 G327 I328 F347
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0080008 Cul4-RING E3 ubiquitin ligase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4a0l, PDBe:4a0l, PDBj:4a0l
PDBsum4a0l
PubMed22118460
UniProtQ2YDS1|DDB2_DANRE DNA damage-binding protein 2 (Gene Name=ddb2)

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