Structure of PDB 4a09 Chain B

Receptor sequence
>4a09B (length=354) Species: 7955 (Danio rerio) [Search protein sequence]
QTSILHYIYKSSLGQSIHAQLRQCLQEPFIRSLKSYKLHRTASPFDRRVT
SLEWHPTHPTTVAVGSKGGDIILWDYDVQNKTSFIQGMGPGDAITGMKFN
QFNTNQLFVSSIRGATTLRDFSGSVIQVFAKTDSWDYWYCCVDVSVSRQM
LATGDSTGRLLLLGLDGHEIFKEKLHKAKVTHAEFNPRCDWLMATSSVDA
TVKLWDLRNIKDKNSYIAEMPHEKPVNAAYFNPTDSTKLLTTDQRNEIRV
YSSYDWSKPDQIIIHPHRQFQHLTPIKATWHPMYDLIVAGRYPDDQLLLN
DKRTIDIYDANSGGLVHQLRDPNAAGIISLNKFSPTGDVLASGMGFNILI
WNRE
3D structure
PDB4a09 The Molecular Basis of Crl4(Ddb2/Csa) Ubiquitin Ligase Architecture, Targeting, and Activation
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R148 K168 G192 W239 K280 V299 P326 Q345 Q372 H373 R47 K67 G91 W138 K179 V198 P225 Q244 Q271 H272
BS02 dna B R369 F371 Q372 Y393 R404 G427 I428 F447 R268 F270 Q271 Y292 R303 G326 I327 F346
BS03 CA B H283 Y331 H182 Y230
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
Biological Process
GO:0006281 DNA repair
Cellular Component
GO:0005634 nucleus
GO:0080008 Cul4-RING E3 ubiquitin ligase complex

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Cellular Component
External links
PDB RCSB:4a09, PDBe:4a09, PDBj:4a09
PDBsum4a09
PubMed22118460
UniProtQ2YDS1|DDB2_DANRE DNA damage-binding protein 2 (Gene Name=ddb2)

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