Structure of PDB 3zzf Chain B

Receptor sequence
>3zzfB (length=289) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
GFSATRSTVIQLLNNISTKREVEQYLKYFTSVSQQQFAVIKVGGAIISDN
LHELASCLAFLYHVGLYPIVLHGTGPQVNGRLEAQGIEPDYIDGIRITDE
HTMAVVRKCFLEQNLKLVTALEQLGVRARPITSGVFTADYLDKDKYKLVG
NIKSVTKEPIEASIKAGALPILTSLAETASGQMLNVNADVAAGELARVFE
PLKIVYLNEKGGIINGSTGEKISMINLDEEYDDLMKQSWVKYGTKLKIRE
IKELLDYLPRSSSVAIINVQDLQKELFTDSGAGTMIRRG
3D structure
PDB3zzf Insight on an Arginine Synthesis Metabolon from the Tetrameric Structure of Yeast Acetylglutamate Kinase
ChainB
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K103 G106 G137 D251 K309
Catalytic site (residue number reindexed from 1) K41 G44 G75 D189 K247
Enzyme Commision number 1.2.1.38: N-acetyl-gamma-glutamyl-phosphate reductase.
2.7.2.8: acetylglutamate kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NLG B G135 T136 G137 R158 N247 V248 N249 A250 G73 T74 G75 R96 N185 V186 N187 A188 MOAD: Ki=400mM
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:3zzf, PDBe:3zzf, PDBj:3zzf
PDBsum3zzf
PubMed22529931
UniProtQ01217|ARG56_YEAST Protein ARG5,6, mitochondrial (Gene Name=ARG5,6)

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