Structure of PDB 3zxt Chain B

Receptor sequence
>3zxtB (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
ENVDDYYDTGEELGSGQFAVVKKCREKSTGLQYAAKFIKKRRTKSRRGVS
REDIEREVSILKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAE
KLTEEEATEFLKQILNGVYYLHSLQIAHFDLKPENIMLLDRNVPKPRIKI
IDFGLAHKIDTPEFVAPEIVNYEPLGLEADMWSIGVITYILSGASPFLGD
TKQETLANVSAVNYEFEDEYFSALAKDFIRRLLVKDPKKRMTIQDSLQHP
WIK
3D structure
PDB3zxt A Journey Through the Dap Kinase Architecture
ChainB
Resolution2.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D139 K141 E143 N144 D161 T180
Catalytic site (residue number reindexed from 1) D130 K132 E134 N135 D152 T161
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG B N144 D161 N135 D152
BS02 ACP B G22 Q23 F24 V27 A40 K42 I77 V96 E100 M146 I160 D161 G16 Q17 F18 V21 A34 K36 I70 V89 E93 M137 I151 D152
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3zxt, PDBe:3zxt, PDBj:3zxt
PDBsum3zxt
PubMed
UniProtP53355|DAPK1_HUMAN Death-associated protein kinase 1 (Gene Name=DAPK1)

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