Structure of PDB 3zoa Chain B

Receptor sequence
>3zoaB (length=571) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
HPNAEDFGHARTLPTDTNWFKHAVFYEVLVRAFYDSNADGIGDLRGLTEK
LDYIKWLGVDCLWLPPFYDSPLRDGGYDIRDFYKVLPEFGTVDDFVTLLD
AAHRRGIRIITDLVMNHTSDQHEWFQESRHNPDGPYGDFYVWSDTSDRYP
DARIIFVDTEESNWTFDPVRRQFYWHRFFSHQPDLNYDNPAVQEAMLDVL
RFWLDLGIDGFRLDAVPYLFEREGTNCENLPETHAFLKRCRKAIDDEYPG
RVLLAEANQWPADVVAYFGDPDTGGDECHMAFHFPLMPRIFMAVRRESRF
PISEILAQTPPIPDTAQWGIFLRNHDELTLEMVTDEERDYMYAEYAKDPR
MKANVGIRRRLAPLLENDRNQIELFTALLLSLPGSPVLYYGDEIGMGDII
WLGDRDSVRTPMQWTPDRNAGFSKATPGRLYLPPNQDAVYGYHSVNVEAQ
LDSSSSLLNWTRNMLAVRSRHDAFAVGTFRELGGSNPSVLAYIREVTRQQ
GDGGAKTDAVLCVNNLSRFPQPIELNLQQWAGYIPVEMTGYVEFPSIGQL
PYLLTLPGHGFYWFQLREPDP
3D structure
PDB3zoa The Structure of the Mycobacterium Smegmatis Trehalose Synthase Reveals an Unusual Active Site Configuration and Acarbose-Binding Mode.
ChainB
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D128 R228 D230 E272 H341 D342
Catalytic site (residue number reindexed from 1) D112 R212 D214 E256 H325 D326
Enzyme Commision number 3.2.1.1: alpha-amylase.
5.4.99.16: maltose alpha-D-glucosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC B R534 F535 R518 F519
BS02 CA B N132 D200 Y234 L235 E237 N116 D184 Y218 L219 E221
BS03 MG B D51 N53 D55 I57 D59 D35 N37 D39 I41 D43
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004556 alpha-amylase activity
GO:0005509 calcium ion binding
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016853 isomerase activity
GO:0046872 metal ion binding
GO:0047471 maltose alpha-D-glucosyltransferase activity
Biological Process
GO:0000023 maltose metabolic process
GO:0000272 polysaccharide catabolic process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0005978 glycogen biosynthetic process
GO:0005991 trehalose metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3zoa, PDBe:3zoa, PDBj:3zoa
PDBsum3zoa
PubMed23735230
UniProtA0R6E0|TRES_MYCS2 Trehalose synthase/amylase TreS (Gene Name=treS)

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