Structure of PDB 3zk4 Chain B

Receptor sequence

>3zk4B (length=571) Species: 3873 (Lupinus luteus)

DEHAYIKATPNVLGFEGHYTEWVTLQYSNNKPSIDDWIGVFSPANFSAST
CPGENKMTNPPFLCSAPIKFQYANFSSHSYKDTGKGSLKLQLINQRSDFS
FALFTGGLTNPKLIAVSNKVSFVNPNAPVYPRLAQGKTWDEITVTWTSGY
DINDAEPFVEWGPKEGNLVKTPAGTLTFDRNTMCGAPARTVGWRDPGYIH
TSFLKELWPNREYTYKLGHRLFNGTTIWSKEYHFKASPYPGQSSVQRVVI
FGDMGKAEADGSNEYNNFQPGSLNTTKQIIQDLEDIDIVFHIGDLCYANG
YISQWDQFTAQIEPIASTVPYMTASGNHERDWPGTGSFYGNLDSGGECGV
PAQTMFFVPAENREKFWYSTDYGMFRFCIAHTELDWRKGTEQYEFIEKCL
ASVDRQKQPWLIFLAHRVLGYSSAGFYVQEGSFEEPMGREDLQHLWQKYK
VDIAMYGHVHNYERTCPIYQNVCTNKEKHNYKGNLNGTIHVVVGGGGASL
AEFAPINTTWSIFKDHDFGFVKLTAFDHSNLLLEYRKSSDGQVYDSFTIS
RDYRDILACSVDSCPTTTLAS

3D structure

• PDB: 3zk4 The Structure of a Purple Acid Phosphatase Involved in Plant Growth and Pathogen Defence Exhibits a Novel Immunoglobulin-Like Fold
• Chain: B
• Resolution: 1.65 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): D272 D313 Y316 N346 H347 H435 F445 Y446 H477 H479
• Catalytic site (residue number reindexed from 1): D253 D294 Y297 N327 H328 H416 F426 Y427 H458 H460
• Enzyme Commision number: 3.1.3.2: acid phosphatase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FE	B	D272 D313 Y316 H479	D253 D294 Y297 H460
BS02	MN	B	D313 N346 H435 H477	D294 N327 H416 H458
BS03	PO4	B	D313 Y316 N346 H347 H477 H479	D294 Y297 N327 H328 H458 H460

Gene Ontology

Molecular Function

• GO:0003993 acid phosphatase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3zk4, PDBe:3zk4, PDBj:3zk4
• PDBsum: 3zk4
• PubMed: 25075326
• UniProt: Q8VX11