Structure of PDB 3x1i Chain B

Receptor sequence
>3x1iB (length=237) Species: 9606 (Homo sapiens) [Search protein sequence]
DLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVIYDMNSLMMGEVA
IRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYT
MLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALE
LDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPES
SQLFAKLLQKMTDLRQIVTEHVQLLQVIKKPLLQEIY
3D structure
PDB3x1i Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 66B B G284 C285 R288 S289 I326 L330 I341 G56 C57 R60 S61 I98 L102 I113
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3x1i, PDBe:3x1i, PDBj:3x1i
PDBsum3x1i
PubMed25785518
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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