Structure of PDB 3x1h Chain B

Receptor sequence
>3x1hB (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
SADLRALAKHLYDSYIKSFPLTKAKARAILTGKDKSPFVIYDMNSLMMGE
DKIKFKHITPKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQ
VTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFM
EPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLL
QALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTHPLLQ
EIYK
3D structure
PDB3x1h Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5OX B I281 G284 C285 R288 S289 L330 V339 L340 I341 M364 I67 G70 C71 R74 S75 L116 V125 L126 I127 M150
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3x1h, PDBe:3x1h, PDBj:3x1h
PDBsum3x1h
PubMed25785518
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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