Structure of PDB 3wxb Chain B

Receptor sequence
>3wxbB (length=252) Species: 9031 (Gallus gallus) [Search protein sequence]
LRVRSVLVTGANRGIGLGFVQHLLALSNPPEWVFATCRDPKGQRAQELQK
LASKHPNLVIVPLEVTDPASIKAAAASVGERLKGSGLNLLINNAGIARAN
TIDNETLKDMSEVYTTNTIAPLLLSQAFLPMLKKAAQEGLSCSKAAIINI
SSTAGSIQDLYLWQYGQALSYRCSKAALNMLTRCQSMGYREHGIFCVALH
PGWVKTDMGGTLEDKSRVTVDESVGGMLKVLSNLSEKDSGAFLNWEGKVM
AW
3D structure
PDB3wxb A novel NAD(P)H-dependent carbonyl reductase specifically expressed in the thyroidectomized chicken fatty liver: catalytic properties and crystal structure.
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.1.1.184: carbonyl reductase (NADPH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP B G13 N15 R16 I18 R41 E67 V68 N96 A97 G98 I99 S159 Y178 K182 P208 G209 W210 V211 T213 M215 G10 N12 R13 I15 R38 E64 V65 N93 A94 G95 I96 S152 Y171 K175 P201 G202 W203 V204 T206 M208
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3wxb, PDBe:3wxb, PDBj:3wxb
PDBsum3wxb
PubMed26206323
UniProtF1N9C1

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