Structure of PDB 3wv6 Chain B

Receptor sequence
>3wv6B (length=284) Species: 9606 (Homo sapiens) [Search protein sequence]
GSQAPYLSPAVPFSGTIQGGLQDGLQITVNGTVLSSSGTRFAVNFQTGFS
GNDIAFHFNPRFEDGGYVVCNTRQNGSWGPEERKTHMPFQKGMPFDLCFL
VQSSDFKVMVNGILFVQYFHRVPFHRVDTISVNGSVQLSYISFQHMYPHP
AYPMPFITTILGGLYPSKSILLSGTVLPSAQSFHINLCSGNHIAFHLNPR
FDENAVVRNTQIDNSWGSEERSLPRKMPFVRGQSFSVWILCEAHCLKVAV
DGQHLFEYYHRLRNLPTINRLEVGGDIQLTHVQT
3D structure
PDB3wv6 X-ray structure of a protease-resistant mutant form of human galectin-9 having two carbohydrate recognition domains with a metal-binding site
ChainB
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC B R65 E85 R61 E81
BS02 GAL B H61 R65 N75 W82 E85 H57 R61 N71 W78 E81
BS03 GLC B R239 E258 R260 R200 E219 R221
BS04 GAL B H235 R239 N248 W255 E258 H196 R200 N209 W216 E219
BS05 ZN B D100 C102 H188 H320 D96 C98 H149 H281
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3wv6, PDBe:3wv6, PDBj:3wv6
PDBsum3wv6
PubMed28687490
UniProtO00182|LEG9_HUMAN Galectin-9 (Gene Name=LGALS9)

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