Structure of PDB 3wqy Chain B

Receptor sequence
>3wqyB (length=905) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence]
MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSF
IGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIAS
IADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAH
HAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPC
LEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERF
VWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGI
MGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFM
LGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFE
FDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYD
SHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNE
YPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYL
IANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHH
SATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEM
LANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDV
QACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERL
LREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILME
RAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVT
FSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRF
LSEHE
3D structure
PDB3wqy The selective tRNA aminoacylation mechanism based on a single G.U pair
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.7: alanine--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A5A B R128 H141 L142 F145 M147 W191 E209 V210 T212 D242 T243 G244 G246 R128 H141 L142 F145 M147 W191 E209 V210 T212 D242 T243 G244 G246
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004813 alanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006419 alanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3wqy, PDBe:3wqy, PDBj:3wqy
PDBsum3wqy
PubMed24919148
UniProtO28029|SYA_ARCFU Alanine--tRNA ligase (Gene Name=alaS)

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