Structure of PDB 3wmx Chain B

Receptor sequence
>3wmxB (length=308) Species: 381666 (Cupriavidus necator H16) [Search protein sequence]
PKILIVGANGQIGSELALALAERYGRTNVITSDVVPTGRHVHLTHEMLNA
TDRGELATVVERHGITQVYLLAAALSATGEKAPQWAWNLNMTSLLNVLEL
ARQTGLERVFWPSSIAAFGPTTPAGQTPQKTVMEPTTVYGISKQAGEGWC
RWYHANHGVDVRSVRYPGLISHKTPPGGGTTDYAVDIFHAAVTGEPYTCF
LKEDEALPMMYMPDAIRATIELMEAPADKLSERGSYNIAGMSFTPAQIAA
AIREQVPGFQIRYEPDYRQAIAQGWPDSIDDSVARADWGWKAQYGLKEMV
ADMLANLK
3D structure
PDB3wmx Binding of NAD+ and L-Threonine Induces Stepwise Structural and Flexibility Changes in Cupriavidus necator L-Threonine Dehydrogenase
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G12 G15 Q16 I17 D38 V39 N54 A55 L76 A77 P117 S119 Y144 K148 Y171 L174 G7 G10 Q11 I12 D33 V34 N49 A50 L71 A72 P112 S114 Y139 K143 Y166 L169
BS02 THR B L80 S81 Y144 G184 T185 T186 L75 S76 Y139 G179 T180 T181
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008743 L-threonine 3-dehydrogenase activity
GO:0016853 isomerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006567 threonine catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3wmx, PDBe:3wmx, PDBj:3wmx
PDBsum3wmx
PubMed24558034
UniProtQ0K312

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